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  1. Semaglutide linked to 26% lower 5-year predicted dementia risk (wiley.com)
    ×2.19 1 | 218 points by randycupertino 4 hours ago | 146 comments | ▲ ▼ ??? ???
  2. AI Isn't Outthinking Mathematicians. It's Out-Remembering Them (davidepiffer.com)
    ×3.73 1 | 217 points by rzk 2 hours ago | 186 comments | ▲ ▼ ??? ???
  3. So How Is AI Drug Discovery Doing, Really? (science.org)
    ×1.73 2 | 29 points by AnodicElegy 1 hour ago | 14 comments | ▲ ▼ ??? ???
  4. The First At-Home Test for Infected Ticks Could Improve Lyme Disease Diagnosis (smithsonianmag.com)
    ×1.43 4 | 156 points by gmays 6 hours ago | 54 comments | ▲ ▼ ??? ???
  5. First human trials of designer protein therapies stun US neuroscientists (acs.org)
    ×1.40 12 | 17 points by gradus_ad 1 hour ago | 27 comments | ▲ ▼ ??? ???
  6. Auto-research with codex: How I achieved a 232x Faster Kernel (bearblog.dev)
    ×2.09 1 | 322 points by tosh 9 hours ago | 82 comments | ▲ ▼ ??? ???
  7. RISC-V: They Should Have Known Better (dmitry.gr)
    ×2.08 1 | 139 points by dmitrygr 5 hours ago | 257 comments | ▲ ▼ ??? ???
  8. A Spectre Is Haunting Unicode (dampfkraft.com)
    ×2.06 5 | 100 points by sensanaty 5 hours ago | 23 comments | ▲ ▼ ??? ???
  9. Working with AI Feels More Like Leadership Than Coding (bargi.org)
    ×2.56 9 | 204 points by allenb 9 hours ago | 144 comments | ▲ ▼ ??? ???
  10. Voltair (YC W26) Is Hiring a Test Flight Engineer (ycombinator.com)
    1 hour ago | discuss | ▲ ▼ ??? ???
  11. Could a computer scientist build a brain? (stankerstjens.github.io)
    ×1.32 14 | 65 points by ogundipeore 6 hours ago | 36 comments | ▲ ▼ ??? ???
  12. 2D Gaussian Splatting for Bézier Spline Line Art Vectorization (disneyresearch.com)
    ×0.82 15 | 42 points by Jimmc414 5 hours ago | 4 comments | ▲ ▼ ??? ???
  13. A controversial Alzheimer's surgery is said to reverse symptoms (nature.com)
    ×2.63 9 | 113 points by jeffreyrogers 3 hours ago | 41 comments | ▲ ▼ ??? ???
  14. The mathematical beauty of hyperbezier curves (linebender.org)
    ×1.51 15 | 153 points by raphlinus 11 hours ago | 21 comments | ▲ ▼ ??? ???
  15. Show HN: Eigendrum - Draw any shape and hear what it sounds like as a drum (baselashraf81.github.io)
    ×1.51 16 | 156 points by BaselAshraf81 12 hours ago | 81 comments | ▲ ▼ ??? ???
  16. BriskDB (github.com/schapman1974)
    ×1.11 14 | 12 points by schapman1974 2 hours ago | 2 comments | ▲ ▼ ??? ???
  17. The other Sean Byrne doesn't exist (conic.al)
    ×1.89 7 | 343 points by rdl 15 hours ago | 170 comments | ▲ ▼ ??? ???
  18. The Dutch Community Where People Live on Strips of Land in a Lake (core77.com)
    ×2.25 9 | 61 points by Bowes-Lyon 3 hours ago | 33 comments | ▲ ▼ ??? ???
  19. Printytron – Type it. 3D Print it (printytron.com)
    ×1.35 26 | 29 points by statenjason 5 hours ago | 1 comments | ▲ ▼ ??? ???
  20. Going Dark, and the era of law enforcement hacking (cryptographyengineering.com)
    ×2.20 19 | 438 points by vslira 23 hours ago | 233 comments | ▲ ▼ ??? ???
  21. Pizza Box Project Stack (cblgh.org)
    ×0.19 77 | 3 points by surprisetalk 1 hour ago | discuss | ▲ ▼ ??? ???
  22. Yadda 3.0.0: BDD in the Age of AI Agents (stephen-cresswell.com)
    ×0.75 10 | 46 points by scresswell 6 hours ago | 24 comments | ▲ ▼ ??? ???
  23. The Color of White Light (ludens.cl)
    ×1.05 25 | 75 points by xk3 10 hours ago | 40 comments | ▲ ▼ ??? ???
  24. Using GCC's Nested Functions with Wide Pointers and No Trampolines II (uecker.codeberg.page)
    ×0.87 34 | 77 points by uecker 12 hours ago | 42 comments | ▲ ▼ ??? ???
  25. Thunderbird's Desktop Calendar Visual Redesign (thunderbird.net)
    ×2.13 11 | 25 points by birdculture 2 hours ago | 6 comments | ▲ ▼ ??? ???
  26. In 1962, Egypt's Missile Program Lost Its Key Scientist Without a Trace (popularmechanics.com)
    ×1.13 39 | 110 points by bookofjoe 15 hours ago | 69 comments | ▲ ▼ ??? ???
  27. Möbius Strips and Differential Equations (hidden-phenomena.com)
    ×0.97 23 | 52 points by mbustamanter 8 hours ago | 9 comments | ▲ ▼ ??? ???
  28. Qwen 3.8 27B (huggingface.co)
    ×4.94 7 | 1331 points by erdaltoprak 1 day ago | 758 comments | ▲ ▼ ??? ???
  29. Firefox is now the last major browser that still supports uBlock Origin (pcworld.com)
    ×11.57 14 | 1608 points by DemiGuru 1 day ago | 609 comments | ▲ ▼ ??? ???
  30. Robot Videos: Heavy Lift Cargo Drones, Grippers, More (ieee.org)
    ×0.26 51 | 7 points by rbanffy 3 hours ago | discuss | ▲ ▼ ??? ???
  31. Why tech bosses keep sharing their manifestos about AI (bbc.com)
    ×1.17 9 | 4 points by tcp_handshaker 48 minutes ago | 2 comments | ▲ ▼ ??? ???
  32. T3X/0 a Minimal Procedural Language (t3x.org)
    ×0.89 34 | 32 points by AlexeyBrin 8 hours ago | discuss | ▲ ▼ ??? ???
  33. Show HN: ThoughtDAG – An editable context graph for LLM conversations (chenxiachan.github.io)
    ×1.15 41 | 97 points by chatchan 15 hours ago | 47 comments | ▲ ▼ ??? ???
  34. Europe's scorched landscapes seen from space after summer heatwaves (bbc.com)
    ×3.26 31 | 84 points by blondie9x 2 hours ago | 63 comments | ▲ ▼ ??? ???
  35. Xorshift Generators (alanzucconi.com)
    ×0.69 28 | 29 points by tobr 7 hours ago | 21 comments | ▲ ▼ ??? ???
  36. Job Recession in Higher Education (gadlevanon.substack.com)
    ×2.54 | 5 points by paulpauper 1 hour ago | discuss | ▲ ▼ ??? ???
  37. IBM Simon (1994): the original smartphone, explained in its own ad [video] (youtube.com)
    ×1.98 11 | 7 points by kls0e 1 hour ago | discuss | ▲ ▼ ??? ???
  38. A Planet Position Widget (leancrew.com)
    ×0.28 66 | 11 points by speckx 6 hours ago | 1 comments | ▲ ▼ ??? ???
  39. Understanding WCAG 2.2 as ePub and PDF (doeken.org)
    ×0.72 51 | 51 points by doekenorg 13 hours ago | 3 comments | ▲ ▼ ??? ???
  40. Magnitude 7.7 Earthquake – 68 km NNW of Ende, Indonesia (usgs.gov)
    ×1.35 13 | 210 points by Bender 19 hours ago | 55 comments | ▲ ▼ ??? ???
  41. GLM-5.3: Frontier coding with emergent cyber capabilities (z.ai)
    ×4.42 3 | 1127 points by pella 1 day ago | 554 comments | ▲ ▼ ??? ???
  42. Unearthing a 31 year old Easter egg in Ecco the Dolphin (32bits.substack.com)
    ×1.27 59 | 116 points by bbayles 22 hours ago | 30 comments | ▲ ▼ ??? ???
  43. I turned my RSS feeds into an e-ink newspaper to stop reading on my phone (heyjonny.dev)
    ×1.30 54 | 216 points by speckx 1 day ago | 95 comments | ▲ ▼ ??? ???
  44. Show HN: Quasicrystals Animation Playground with WebXR (hypnagogic-quasicrystals.github.io)
    ×0.66 3 | 33 points by r34 6 hours ago | 9 comments | ▲ ▼ ??? ???
  45. Brain turns listening inward during REM sleep, EEG recordings suggest (medicalxpress.com)
    ×1.32 7 | 45 points by gmays 7 hours ago | 15 comments | ▲ ▼ ??? ???
  46. Bedtime Procrastination (wikipedia.org)
    ×3.48 26 | 12 points by sand33pn 1 hour ago | 2 comments | ▲ ▼ ??? ???
  47. Racket v9.3 (racket-lang.org)
    ×1.70 63 | 125 points by privong 1 day ago | 15 comments | ▲ ▼ ??? ???
  48. Introducing Toast 1 (mixedbread.com)
    ×1.17 46 | 216 points by mplappert 1 day ago | 65 comments | ▲ ▼ ??? ???
  49. Ultraviolet Bird Photography (uvbirds.com)
    ×1.13 57 | 165 points by EndXA 1 day ago | 26 comments | ▲ ▼ ??? ???
  50. Why does Opus 5 feel worse to work with? (mun-logadan.github.io)
    ×4.53 8 | 924 points by numeri 1 day ago | 826 comments | ▲ ▼ ??? ???
  51. This Hi-Fi Tape Recorder Changed Radio Forever (ieee.org)
    ×0.73 64 | 61 points by Jimmc414 19 hours ago | 18 comments | ▲ ▼ ??? ???
  52. Peer-reviewed study of 443,000 Backblaze drives ranks HGST most reliable (tomshardware.com)
    ×1.79 24 | 12 points by sbulaev 2 hours ago | 3 comments | ▲ ▼ ??? ???
  53. Super Mario Derivations (fzakaria.com)
    ×1.18 46 | 125 points by domenkozar 23 hours ago | 18 comments | ▲ ▼ ??? ???
  54. Show HN: Silent Shark – tactical map-based WWII submarine sim (silentshark.app)
    ×1.10 37 | 66 points by epaga 15 hours ago | 31 comments | ▲ ▼ ??? ???
  55. Simplifying and Refactoring Introductory Calculus (2018) (arxiv.org)
    ×1.24 33 | 124 points by E-Reverance 20 hours ago | 74 comments | ▲ ▼ ??? ???
  56. Planes With Same Call Sign at PHX – one departing, one arriving (nytimes.com)
    ×1.42 24 | 4 points by jsrozner 1 hour ago | 1 comments | ▲ ▼ ??? ???
  57. The Ploopy A+ Trackball Is Here (ploopy.co)
    ×1.28 26 | 129 points by big_toast 19 hours ago | 64 comments | ▲ ▼ ??? ???
  58. Firefox stunts on Edge as Microsoft gears up to neuter adblockers (pcgamer.com)
    ×2.39 2 | 4 points by latein 1 hour ago | 2 comments | ▲ ▼ ??? ???
  59. Google is making private AI practical with homomorphic encryption (blog.google)
    ×2.41 5 | 474 points by u1hcw9nx 1 day ago | 276 comments | ▲ ▼ ??? ???
  60. Turbo Pascal on CP/M, MSX-DOS and MS-DOS (hansotten.com)
    ×0.82 66 | 103 points by rbanffy 1 day ago | 44 comments | ▲ ▼ ??? ???
  61. A 25-year-old video patent just expired, ending a legal headache for Linux (xda-developers.com)
    ×2.02 10 | 14 points by theanonymousone 3 hours ago | 1 comments | ▲ ▼ ??? ???
  62. Show HN: Mole – Deep research agent for your terminal (github.com/lajosdeme)
    ×0.79 60 | 86 points by lajosdeme 1 day ago | 13 comments | ▲ ▼ ??? ???
  63. Show HN: I evaluated file, vector, graph and RL based memory frameworks (pinglin.tw)
    ×1.56 37 | 10 points by pinglin 5 hours ago | discuss | ▲ ▼ ??? ???
  64. HyperOSUnfucker is an Android app that unlocks hidden system performance (github.com/Enki013)
    ×1.00 75 | 10 points by Bluestein 9 hours ago | 2 comments | ▲ ▼ ??? ???
  65. Show HN: Deltix – AI Driven Testing (deltix.ai)
    ×0.72 56 | 44 points by oneounceman 17 hours ago | 11 comments | ▲ ▼ ??? ???
  66. OpenAI talent exodus raises 'huge red flag' ahead of IPO (cnbc.com)
    ×2.83 17 | 20 points by pseudolus 4 hours ago | 3 comments | ▲ ▼ ??? ???
  67. Seven books I keep close because I love them (plover.com)
    ×1.85 4 | 365 points by surprisetalk 1 day ago | 168 comments | ▲ ▼ ??? ???
  68. RustDesk now supports true unattended remote access on Wayland (rustdesk.com)
    ×1.63 4 | 332 points by rustdesk 1 day ago | 148 comments | ▲ ▼ ??? ???
  69. DHS demands AAMVA's national commercial driver database (papersplease.org)
    ×2.33 35 | 8 points by iamnothere 1 hour ago | 1 comments | ▲ ▼ ??? ???
  70. Coin-sized device can hack a Boeing 737 (wired.com)
    ×1.34 9 | 119 points by _tk_ 15 hours ago | 95 comments | ▲ ▼ ??? ???
  71. The Three AI Pills (thezvi.substack.com)
    ×1.89 8 | 4 points by stuartmemo 1 hour ago | discuss | ▲ ▼ ??? ???
  72. The Mysterious Art of Conducting (theatlantic.com)
    ×2.06 12 | 5 points by anarbadalov 1 hour ago | discuss | ▲ ▼ ??? ???
  73. Show HN: Ember – Redshift safe color palettes (github.com/carpdiem)
    ×1.07 39 | 104 points by carpdiem 1 day ago | 22 comments | ▲ ▼ ??? ???
  74. Gemini 3.7 Flash (blog.google)
    ×3.28 11 | 957 points by thisisauserid 2 days ago | 485 comments | ▲ ▼ ??? ???
  75. Scientists increasingly depend on 'black-box' tools they cannot control (exeter.ac.uk)
    ×2.09 16 | 14 points by geox 4 hours ago | discuss | ▲ ▼ ??? ???
  76. Every Fucking Website (2020) (lxe.github.io)
    ×4.61 43 | 828 points by doubletwoyou 1 day ago | 474 comments | ▲ ▼ ??? ???
  77. Maximizing the value of your Claude Code sessions (claude.com)
    ×2.03 1 | 298 points by twapi 1 day ago | 170 comments | ▲ ▼ ??? ???
  78. z486: A 486-Class Pipelined FPGA CPU with Integrated Floating-Point (nand2mario.github.io)
    ×1.02 71 | 16 points by matt_d 13 hours ago | 8 comments | ▲ ▼ ??? ???
  79. Secondhand book sales are booming. Is it because of AI? (bbc.co.uk)
    ×2.07 56 | 62 points by m-i-l 6 hours ago | 68 comments | ▲ ▼ ??? ???
  80. Gödel, Escher, Elisp: The Beauty of Macros (chiply.dev)
    ×1.09 50 | 100 points by JNRowe 1 day ago | 37 comments | ▲ ▼ ??? ???
  81. TreasuryDirect: Prepare for ID.me – Your New Way to Log In (treasurydirect.gov)
    ×1.88 70 | 46 points by Mindless2112 2 hours ago | 41 comments | ▲ ▼ ??? ???
  82. Show HN: A website for exploring historical photographs of my city (maprva.org)
    ×0.59 55 | 32 points by uneekname 18 hours ago | 12 comments | ▲ ▼ ??? ???
  83. Differential Heuristics (redblobgames.com)
    ×1.08 50 | 134 points by ibobev 1 day ago | 8 comments | ▲ ▼ ??? ???
  84. AI by Hand (byhand.ai)
    ×2.14 15 | 346 points by sans_souse 1 day ago | 29 comments | ▲ ▼ ??? ???
  85. A humble cabbage became one of the Forbidden City’s treasures (2025) (cnn.com)
    ×0.71 61 | 69 points by dude250711 1 day ago | 9 comments | ▲ ▼ ??? ???
  86. Ntfy – open-source Push to Mobile (ntfy.sh)
    ×1.63 52 | 107 points by Fake4d 1 day ago | 50 comments | ▲ ▼ ??? ???
  87. Every fucking website: 2026 edition (tngl.io)
    ×4.25 27 | 106 points by nerdypepper 1 day ago | 31 comments | ▲ ▼ ??? ???
  88. AI Model Atlas – visualizing populations of ML models as interconnected 3D graph (cosmograph.app)
    ×0.69 69 | 64 points by bj-rn 1 day ago | 8 comments | ▲ ▼ ??? ???
  89. Show HN: LuaCAD – Parametric CAD Scripted in Lua (ad-si.com)
    ×0.97 34 | 100 points by adius 1 day ago | 20 comments | ▲ ▼ ??? ???
  90. New Lower and Upper Bounds for the Grothendieck Constant (arxiv.org)
    ×0.55 60 | 49 points by surprisetalk 1 day ago | 10 comments | ▲ ▼ ??? ???